An Age-Old Question: Warfarin or a Direct Oral Anticoagulant in Frail Adults?

It is now uncommon to see warfarin therapy initiated for stroke prevention. However, quality patient care is never a “one-size-fits-all” approach.  New evidence from the FRAIL-AF trial suggests that some of our most vulnerable older adults might be better off maintained on a vitamin K antagonist rather than (automatically) switched to a direct oral anticoagulation (DOAC).  

Guest Author:  Matthew Cantrell, PharmD, BCPS

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