iForumRx.org

The Kidney Disease: Improving Global Outcomes (KDIGO) guidelines were recently updated with a focus on kidney health in patients with diabetes.  The updated guidelines include recommendations on screening, prevention, and treatment of chronic kidney disease (CKD), including the use of SGLT2 inhibitors, finerenone, and ACE inhibitors or ARBs.  The written commentary posted on the iForumRx website provides a succinct summary of the Top Ten Things Every Clinician Should Know.

Guest Authors:  Kara Olstad, PharmD; Gurminder Sanghera, BSc, PharmD; and Darren Grabe, PharmD

Music by Good Talk

Would you be willing to pay three times more for a brand-name levothyroxine product than a generic equivalent? Clinical practice guidelines recommend against switching between products. As a result, levothyroxine has higher brand-name product dispensing rates than other medications, costing patients and the healthcare system much more money.

Guest Authors:  Connie Liang, PharmD and Kathleen Pincus, PharmD, BCPS, BCACP

Music by Good Talk

The 2022 AHA/ACC/HFSA Heart Failure Guidelines is a much-needed update and consolidates previously published recommendations. In the written commentary we describe the top ten things every clinician should know about the 2022 AHA/ACC/HFSA Heart Failure Guidelines.  This podcast episode highlights some of the key recommendations from the guidelines and addresses some of the practical implications.

Guest Authors:  Madison Yates, PharmD and Megan Supple, PharmD, BCACP, CPP

Music by Good Talk

Staying abreast of the constant changes to clinical practice guidelines (CPGs) and determining their quality is difficult.  The general consensus in the medical community is that CPGs reduce inappropriate care and improve treatment quality and patient safety. However, concerns have been raised about the reliability, quality, and validity of CPGs. A recently published systematic review critically appraised the quality of published CPGs for the treatment of chronic diseases in primary care.

Guest Authors:  Frank Yu, Pharm.D. and Takova Wallace-Gay, Pharm.D., BCACP

Music by Good Talk

The American Heart Association / American College of Cardiology (AHA/ACC) Task Force recently published the 2018 Guideline on the Management of Blood Cholesterol. The guidelines writing committee had representation from 12 organizations, including the National Lipid Association, American Diabetes Association, and the American Pharmacists Association — all of whom endorsed the guidelines. The previous guidelines (published in 2013) were intended to answer some specific clinical questions and significantly changed our approach to treatment. The 2018 guidelines provide a more comprehensive set of recommendations, akin to the (older) National Heart, Lung, and Blood Institute Adult Treatment Panel (ATP) III guidelines last published in 2002!

Guest Authors:  Dawn Fuke, Pharm.D., BCPS, and Zach Conroy, PharmD, BCACP

Music by Good Talk

The American College of Chest Physicians (ACCP) recently updated their guideline recommendations for the use of antithrombotics for the prevention of stroke in patients with atrial fibrillation (aka the Chest Guidelines).  Find out what's new, who shouldn't receive treatment based on the CHA₂DS₂-VASc score, and why the guideline panel recommends calculating a patient's SAME-TTR score.

Guest Author:  Dylan Lindsay, PharmD

Music by Good Talk