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Should We Hold Our Breath for Vitamin D in COPD?

Should We Hold Our Breath for Vitamin D in COPD?

May 23, 2019

Chronic obstructive pulmonary disease (COPD) exacerbations contribute to mortality, disease progression, worsening quality of life, and increased health care costs. Respiratory tract infections are a common cause of COPD exacerbations.  While prophylactic antibiotics may play a role, vitamin D supplementation is an attractive option by stimulating innate and adaptive immune responses. Although severe vitamin D deficiency (25(OH)D <10 ng/mL) has been associated with more frequent exacerbations and hospitalizations in patients with COPD, it is unclear if supplementation actually reduces exacerbation frequency. A recent meta-analysis provides some data regarding the potential benefits of vitamin D supplement to prevent COPD exacerbations.

Guest Authors:  Jennifer Clements, PharmD, BCPS, BCACP and Lisa Gibbs, PharmD

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Need a VITALity Boost? Rethink Vitamin D and Fish Oil Supplements

Need a VITALity Boost? Rethink Vitamin D and Fish Oil Supplements

April 26, 2019

Vitamin D and fish oil (aka omega-3 fatty acids) were the most widely used vitamin and nutritional supplement in 2011-2012.  Both have been commonly touted for their potential benefits in reducing cancer and cardiovascular disease. While vitamin D and omega-3 fatty acid supplements are wildly popular, the evidence supporting their health benefits is inconclusive and inconsistent. The VITAL study sought to determine whether vitamin D and/or marine omega-3 fatty acids can prevent cardiovascular disease (CVD) and cancer when used by the general population.

Guest Authors:  Anthony M Todd, PharmD; Sean E Smithgall, PharmD, BCACP; and Nicole A Slater, PharmD, BCACP

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