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Does Long-Term Proton Pump Inhibitor Use Pump Up Your Risk of Adverse Effects?

Does Long-Term Proton Pump Inhibitor Use Pump Up Your Risk of Adverse Effects?

May 22, 2020

Many studies have linked proton pump inhibitor (PPI) use to several adverse effects including Clostridium difficile-associated diarrhea, community-acquired pneumonia, bone fractures, and nutritional deficiencies. Other reports have linked PPI use with chronic kidney disease, cognitive decline, myocardial infarction (MI), stroke, and even death. Many patients take PPIs chronically and may be concerned about the risk of these side effects. This poses a challenge for healthcare providers as safety data has been primarily based on retrospective and observational studies. A recently pre-planned analysis using data from the prospective COMPASS study sheds some reassuring light.

Guest Authors:  Hindu Rao, PharmD and Jelena Lewis, PharmD, BCACP, APh

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Fall Risk and Benzos – Is Trazodone Really the Knight in Shining Armor?

Fall Risk and Benzos – Is Trazodone Really the Knight in Shining Armor?

January 18, 2019

Older adults are often tormented by insomnia, pain, and other comorbidities that impact their quality of life.  Medication therapy is often sought to treat and manage these diseases, but healthcare providers often overlook the risks of prescribing medications to patients who are older, frail, and at high risk for falls.  Trazodone is increasingly prescribed for insomnia instead of benzodiazepines presumably because it is considered to be safer and it does not appear on either the Beers or STOP/START lists.  But is trazodone really safer for patients than benzodiazepines?

Guest Authors:  Anthony M. Todd, PharmD and Nicole A Slater, PharmD, BCACP

Music by Good Talk